Showing posts with label ask bill. Show all posts
Showing posts with label ask bill. Show all posts

Seralini Rat Study Retracted




Welcome to another edition of ASK BILL

Bill has been overwhelmed by the number of requests that he receives from people asking him a variety of questions related to science and scams that circulate on the Internet and elsewhere. To manage his time effectively, Bill has decided to do a weekly fun and educational "Ask Bill" segment.

Every Wednesday (or now whenever he has some extra time!), Bill will choose one question from his e-mails and answer another science or hoax question. Get your questions into him ASAP.

This week's question comes from a discussion on GMOs.

The person asked: "What about this study that showed rats getting cancer?"

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What this person is referring to is the now infamous Seralini rat study, which much like the infamous Wakefield autism study, has been heralded as proof by the anti crowd. In scientific/reality arena though it's a constant annoying mosquito.

Here are a couple of problems with the study. First, it's been retracted: http://www.sciencedirect.com/science/article/pii/S0278691512005637

It had problems with the kind of rodent chosen (which is prone to tumors in the first place), the number of rodents in each group (which was very small). Its conclusions have been deemed inconclusive.

One curious thing too is that the data shows something that counters what the anti-gmoers were trying to show. The data was showing a correlation that if you drink pure water, you have a 50% higher mortality rate than if one drank water contaminated with herbicide. Yeah, figure that one out!

 There was a question of ethics as well as Seralini let the tumors grow to an enormous size on the rodents, thus letting them exist in pain for an extended period of time. These animals should've been put to sleep long before they reached a point where tumors were the size of golf balls (which is huge when compared to the size of a body of a rat).

So if you see any website, meme, person using this study (which Seralini has now published in an open-access journal of little relevance or significance)to promote an anti-gmo stance it would be best to pass it off as nonsense. As I've always said, it's fine to hold a particular view, just make sure if you are trying to claim something that it's backed by good evidence and rational thought. Spouting problematic or false info doesn't help your cause.


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*For over 30 years, Bill has been a professional magician and has traveled all across Canada, performing for all ages. Along with his passion for entertaining, Bill is an educator and life-long learner. He continues to study biology, psychology, neuroscience and chemistry.  Bill has also written many articles on science and scams for various blogs, newspapers and other publications.

Visit his business site, Nuvo Entertainment: www.nuvoentertainment.com

Good vs Bad Scientific Studies



Welcome to another edition of ASK BILL!

Bill has been overwhelmed by the number of requests that he receives from people asking him a variety of questions related to science and scams that circulate on the Internet and elsewhere. To manage his time effectively, Bill has decided to do a weekly fun and educational "Ask Bill" segment.

Every Wednesday, Bill will choose one question from his e-mails and answer another science or hoax question. Get your questions into him ASAP.

For this week's ASK BILL, the question is: How does a regular Joe know a good scientific study from a bad one?

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This is a very good question. For laypersons (and even those knowledgeable in the area), trying to find out if a certain study is significant or not can be very confusing. It is not always a simple straight answer as there are many factors to consider. None of the following by themselves is necessarily a sure sign of a bad study, but they can definitely be used for the final consideration, especially if the study has multiple infractions.

The first thing I look at is where the study was published. This is usually a good first indication. If a study is published in a respected scientific journal, its odds of being a good one increases. Of course some bad studies still do get published (some are deliberate hoaxes testing the reliability of said journals and their process), but in time they are often retracted. Searching on Google, the top journals can give you decent resources such as: http://www.scimagojr.com/journalrank.php and https://en.wikipedia.org/wiki/List_of_scientific_journals.

So how does a study get into a respected journal? There is usually a process of evaluation (part of the scientific method) and review. They are often checking the methodology of the study. It's also good to know what type of study it is.

Is it just a review study looking at certain literature? I find these types are only ideal for proposing further studies and not necessarily for drawing any solid conclusion. Now this shouldn't be confused with a meta-analysis, which looks more in-depth at a larger selection of studies to try to determine a reasonable consensus and include more complex data algorithms and thus hold more weight.

Is the study relying on people's reporting/memory recall (which is often fallible, inaccurate, or prone to bias?) Studies that rely on people reporting from memory how they ate 5 years ago (or even 5 months ago) is problematic.

Was it done with experiments on actual people? Many studies are done just in petri dishes or maybe in just certain animals. While these give some good starting points for pursing further studies, they can't always be relied on to discern the reactions within the human body, which is quite different then a petri dish and rats, for example.

How many people were used? A small number of people used in a study can contain a lot of “noise” in regards to more closely representing what can happen in the general public. A study done on 10,000 people is definitely more robust than one done on 10. For example, you could get 3 out of 10 with a reaction and thus conclude a 30% effect. But in the 10,000 study one could find only 100, which then is only 1%.

Was the study blinded and have controls? Although not always possible, being randomized, blinded and having controls to compare to can increase the robustness of the research. Having it where participants do not know if they are getting a placebo or not is ideal, and even more ideal if the researchers are also blind to that fact as well (usually relying on an impartial 3rd party to keep track of that info for later review).

Did the study list conflicts of interest? A good study will list any conflicts of interest that could bias their results. It's about open honesty. One that hides any conflict raises serious red flags. To find a conflict of interest, one may have to do a bit of searching to discover the conflict of interest.

Has it been peer reviewed? With science part of the process is having your research critiqued. This can be others checking your math or even better seeing if when they repeat your experiment, can they replicate the results. This type of review of a study done by competent peers is the reason some studies have been retracted from journals. They found serious flaws in the data, conclusions and reproducibility of the studies. This is why good science can sometimes take a while, but it eventually corrects itself.

I find that media reports on science studies can sometimes misrepresent or exaggerate what is said in an actual study. Headlines are usually done to grab your attention by asserting a certain point like “chocolate can help with_______ study says.” What is often the case is a certain ingredient was found to have an interesting result (quite often in that petri dish we talked about earlier) and that more study is needed. So don't take headlines at face value. It's always a good idea to look at the actual study to see its conclusions (if any), or you could just ASK BILL :) (or any other friend who is proficient in finding out that info).

There are many more factors to consider as well, but just knowing some of the above, one can start to get an understanding of what makes a good study and will hopefully be able to disregard some “bad science.” I hope that answers your question.


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*For over 30 years, Bill has been a professional magician and has traveled all across Canada, performing for all ages. Along with his passion for entertaining, Bill is an educator and life-long learner. He continues to study biology, psychology, neuroscience and chemistry.  Bill has also written many articles on science and scams for various blogs, newspapers and other publications.

Visit his business site, Nuvo Entertainment: www.nuvoentertainment.com


Ask Bill: Drinking Water Safety

Welcome to this week's “ASK BILL”



Bill has been overwhelmed by the number of requests that he receives from people asking him a variety of questions related to science and scams that circulate on the Internet and elsewhere. To manage his time effectively, Bill has decided to do a weekly fun and educational "Ask Bill" segment.

Every Wednesday, Bill will choose one question from his e-mails and answer another science or hoax question. Get your questions into him ASAP.


Check out below for today's question about: "Is city water safe to drink?


Answer:

This week's question is quite interesting.

I was sent a link to a Facebook post about a guy (we will call Jean-Claude) who is complaining about the quality of Windsor's drinking water. I will admit that this is an area I don't have that much knowledge in but I have taken one course on water treatment and health so I have the beginnings of an understanding in this.

Jean-Claude's concern was about the chlorine concentration and also asking “doesn't chlorine lower immune systems, cause cancer and other bad stuff?” He showed a picture of a pool water testing kit which he claimed contained tap water (I will assume he was honest in that claim). He suggested that the concentration was at pool level (1.0..although when I look at the photo it appears to be at 0.5) and also claimed that since people say that you shouldn't drink pool water, then that means the tap water is unsafe. He also made a claim that showering for 15 mins allows for you to absorb 1 gallon of water through the skin by absorption.

There is a lot to go through here but lets get to the short answer first. Is the city water safe to drink? Yes. According to Enwin, “Chlorine is added on a continuous basis to the water leaving the treatment process at a strictly controlled concentration of 1.5 mg/l...the concentration of chlorine in the water is monitored at 18 locations through the distribution system on a daily basis to ensure an adequate concentration is maintained to ensure a safe supply of water to the customers.”

In regards to “lowers immune systems, causes cancer and other bad stuff”: “Health Canada has classified chlorine as unlikely to be carcinogenic to humans. Studies in laboratory animals and humans indicate that chlorine exhibits low toxicity, regardless of the route of exposure (i.e., ingestion, inhalation, dermal). Studies in animals have not been able to identify a concentration of chlorine associated with adverse health effects, in part because of aversion to its taste and odour. No adverse health effects have been observed in humans from consuming water with high chlorine levels (up to 50 mg/L) over a short period of time.” Now some people may not like the taste or smell of chlorine but they can easily install a filter in their home to remove it.

Jean-Claude said you shouldn't drink pool water. This I agree with, but not for the same reasons Jean-Claude thinks. He thinks it's because of the chlorine content. I would say it's because a pool is an open system where it has continual exposure to pollutants. People are swimming in the pool just for starters. Would you want to drink water from a bath tub that had someone was bathing in? I would think it unlikely. A pool also has insects (and other animals including birds), dirt and debris all entering it. Water from your tap is not accessible to the same type of contamination with the exception of water pipe breakage.

So now to the final claim of water absorption through the skin. This is the real reason why I chose this question because I do love laughable claims and this one sure made me laugh that I did my best Mark Wahlberg impression from The Happening.

Seriously though, the skin can absorb some things although it generally is water-resistant but is not water-proof. It's the keratin and sebum (an oil), that helps keep it at bay. You can see its effectiveness when you start to prune when in water too long. So yes it can absorb some water, but it wouldn't be enough to stop you from dehydrating. A gallon of water is a lot of water considering we only need to consume 2.5 quarts, or just over half a gallon, per day depending on individual needs. By Jean-Claude's meter, we would never have to consume water. It is interesting to note that during my looking up info for all this, I found a Danish group did do a study, albeit a small and no control study, to test an old myth of getting drunk by absorption of alcohol through the skin. As you can probably guess, it was confirmed a myth.

Well I hope that answers your question.

Sources:
Enwin FAQ Water
Water Guidelines
Danish Urban Myth

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*For over 30 years, Bill has been a professional magician and has traveled all across Canada, performing for all ages. Along with his passion for entertaining, Bill is an educator and life-long learner. He continues to study biology, psychology, neuroscience and chemistry.  Bill has also written many articles on science and scams for various blogs, newspapers and other publications.

Visit his business site, Nuvo Entertainment: www.nuvoentertainment.com

Climate Change: Ask Bill!



Bill has been overwhelmed by the number of requests that he receives from people asking him a variety of questions related to science and scams that circulate on the Internet and elsewhere. To manage his time effectively, Bill has decided to do a weekly fun and educational "Ask Bill" segment.

Every Wednesday, Bill will choose one question from his e-mails and answer another science or hoax question. Get your questions into him ASAP.


Check out below for today's question about climate change.

“Was this year the hottest July (world average) in our recorded history? Somebody showed me some results that said otherwise. I didn't get to check the sources because I was out and it was on his phone. What do the stats and experts say regarding it and where are these false stats coming from?”

ANSWER:

According to reports from NOAA (http://www.ncdc.noaa.gov/sotc/global/201507), NASA (http://data.giss.nasa.gov/gistemp/tabledata_v3/GLB.Ts+dSST.txt) and JAPAN METEROLOGICAL AGENCY (http://ds.data.jma.go.jp/tcc/tcc/products/gwp/temp/jul_wld.html), this past July (2015) was the hottest recorded.

Some climate change deniers like Joanne Nova (Codling) and Roy Spencer are making claims to the contrary. They are correct in stating that some of the headlines get it wrong, such as those claiming “hottest in 4000 years” because we haven't been recording temperature for that long. The two naysayers though seem to rely on data strictly from UAH satellite data. The problem with this is that satellites do not measure temperature directly, but are inferred from radiance. The UAH data has had problems with the inferred temperatures not matching the actual site surface temperature (http://www.nature.com/nature/journal/v394/n6694/full/394661a0.html).  Thus their claims are suspect and need to be investigated further. Even if it wasn't the hottest July on record, it would not indicate a lack of climate change. Variations go up and down in the short term and that is expected. It's the long term trend that is most important and that clearly shows a warming trend.

It is interesting to note that Joanne Nova has a degree in microbiology and molecular biology and not climatology. Roy Spencer is a meteorologist and not a climatologist. The major difference between the two is time frames. Meteorologists produce forecasts in a window no larger than 10 days and usually localized (weather). Climatologists are concerned with long term climate conditions. When considering sources, one would want it from the highest quality and someone actually in the field of studying climate. 97% of publishing climate scientists agree that humans are causing global warming.

To learn more, I suggest taking this free, self-paced course: Edx Course

I hope this answers your question.

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*For over 30 years, Bill has been a professional magician and has traveled all across Canada, performing for all ages. Along with his passion for entertaining, Bill is an educator and life-long learner. He continues to study biology, psychology, neuroscience and chemistry.  Bill has also written many articles on science and scams for various blogs, newspapers and other publications.

Visit his business site, Nuvo Entertainment: www.nuvoentertainment.com